For patients with moderate aortic stenosis, current guidelines recommend clinical surveillance with echocardiographic assessment every 1 or 2 years. Whether transcatheter aortic-valve replacement ...

In adults with symptomatic severe aortic stenosis, aortic-valve replacement (AVR) relieves symptoms and improves survival. 1-3 Over the past 20 years, more information about the progression of aortic ...

The U.S. health care system still can’t identify medical harm as it occurs. But it’s now possible to develop systems that correct their own deficiencies and make improvements that matter to patients.

When patients, or the parents of patients, become heavily invested in searching for someone to blame for an illness, it’s useful to ask what the search is doing for them. Its accuracy is rarely ...

Although international guidelines recommend intrauterine insemination (IUI) with ovarian stimulation as first-line treatment for unexplained infertility, evidence from comparisons of this method ...

Savolitinib is an oral, potent, highly selective MET–tyrosine kinase inhibitor (TKI). Combination therapy with savolitinib and osimertinib, an epidermal growth factor receptor (EGFR)–TKI, has shown ...

Clinicians in Puerto Rico sometimes provide abortion care to people who travel to obtain services that are no longer provided in their home states. Yet residents themselves face high barriers to care.

Agencies have long relied on civil monetary penalties to address violations of health care and public health regulations. But rules governing federal fines are now in flux.

Patients with extensive-stage small-cell lung cancer have poor outcomes, with a median overall survival of approximately 12 to 13 months. Tarlatamab (a bispecific T-cell engager targeting delta-like ...

Whether endovascular therapy benefits patients with mild acute ischemic stroke from large-vessel occlusion involving the ...

In 2015, pivotal randomized, controlled trials established the benefit of endovascular treatment for acute ischemic stroke due to a large-vessel occlusion. 1,2 The trials showed a major clinical ...