Background To compare relapse and disability outcomes of inebilizumab, azathioprine (AZA), mycophenolate mofetil (MMF) and rituximab (RTX) in maintenance-therapy-naive patients with aquaporin-4 ...
Background To investigate whether exposure to pet hamsters may act as a potential trigger for autoimmune cerebellar ataxia (ACA). Methods We conducted a hospital-based case–control study based on our ...
Background Motor asymmetry is a hallmark of Parkinson’s disease (PD), but ~20% of patients present with symmetric motor signs, which are associated with faster disease progression and poorer ...
is a leading international journal publishing the latest research and reviews on all areas of neurological sciences.
Polyneuropathy, Organomegaly, Endocrinopathy, M-protein and Skin changes (POEMS) syndrome is a rare multisystemic disorder associated with plasma cell dyscrasia, most commonly presenting with ...
Mummery et al 1 outline the recommendations for the appropriate use (AURs) of the amyloid-targeting monoclonal antibody lecanemab in clinical practice in the United Kingdom. These recommendations are ...
Background The pathogenic mechanisms underlying autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy (GFAP-A), a central nervous system disorder associated with GFAP autoimmunity, remain ...
Background Plasma phosphorylated tau (p-tau) 217 test has emerged as a minimally invasive and accessible alternative to positron emission tomography imaging and cerebrospinal fluid analysis for ...
Efgartigimod efficacy and safety in refractory myasthenia gravis: UK’s first real-world experience
Background We report our experience of patients with generalised myasthenia gravis (gMG) treated with efgartigimod, an neonatal Fc receptor antagonist, under the Early Access to Medicine Scheme (EAMS) ...
Myasthenia gravis (MG) treatment’s landscape has dramatically changed with the approval of novel therapeutics that can provide rapid improvement, including in patients typically considered refractory.
Background Patients with functional seizures (FS) can experience dissociation (depersonalisation) before their seizures. Depersonalisation reflects disembodiment, which may be related to changes in ...
Correspondence to Dr Araceli Alonso-Canovas, Movement Disorders Unit, Neurology Department, IRYCIS, Hospital Universitario Ramon y Cajal, Madrid, Madrid, Spain; aracelialonsocanovas{at}gmail.com Our ...
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