Star receiver George Kittle and the San Francisco 49ers face the Buffalo Bills on Sunday at 8:20 p.m. ET at Highmark Stadium.

The San Francisco 49ers and Buffalo Bills will clash on "Sunday Night Football." Here's how to watch the Week 13 NFL game ...

Take a look at the 16 games on the Week 13 NFL schedule this week, starting with three games on Thanksgiving ( Chicago Bears ...

The Green Bay Packers (8-3) returned to Lambeau Field and defeated the San Francisco 49ers (5-6) Sunday, 38-10. It was the ...

Josh Jacobs rushed for three touchdowns to lead the Packers over an injury plagued San Francisco 49ers team from Green Bay.

Week 12 of the NFL season was a fun one. In the 1 p.m. window, we saw the Tennessee Titans upset the Houston Texans, Cooper ...

Saquon Barkley gained 302 total yards from scrimmage and scored two touchdowns as Philadelphia won its seventh straight game ...

Head Coach Mike Macdonald discusses the Seahawks' defensive performance and team development. He emphasizes the importance of ...

In Week 12, there are 11 NFL games today, including the 49ers vs. Packers. Find out the times, channels, and streaming info ...

A pair of NFC West foes face off for the first time on Sunday, Nov. 24 with the Seattle Seahawks welcoming the Arizona ...

On Sunday, the Arizona Cardinals and Seattle Seahawks meet in an exciting NFC West Week 12 matchup at Lumen Field.