September 25, 2025, is being marked as a global VPN Day of Action. The goal is to spotlight how lawmakers are targeting the best VPNs and considering "outright bans" on the privacy tools. The effort ...

First disclosure of a novel mechanism of action for the degradation of TEAD by selectively inducing its proximity to FBXO22 as a targeted molecular glue, leading to strong and rapid degradation of ...

The families of four passengers who died in the accident involving Air India Flight 171 have launched a class action lawsuit against planemaker Boeing, along with Honeywell, citing negligence and a ...

Wegovy (semaglutide) is a prescription drug used for weight loss and to lower the risk of cardiovascular problems in some people. It’s also used to treat metabolic dysfunction-associated ...

Truthout is a vital news source and a living history of political struggle. If you think our work is valuable, support us with a donation of any size. The Trump administration is facing growing ...

High mobility group protein 1 (HMGB1) is a highly conserved chromatin-associated protein that is widely found in eukaryotic cells. Studies have shown that HMGB1 plays an important role in the ...

Please provide your email address to receive an email when new articles are posted on . “This is a really exciting new mechanism of action for our field, hoping to improve functional as well as ...

In this valuable study, the authors show the physiological response and molecular pathway mediating the effect of quinofumelin, a developed fungicide with an unknown mechanism. The authors present ...

A key concept emerging in the treatment of bladder cancer is the idea of broad immune potentiation. Traditional therapies like BCG may fail in some patients because they stimulate a narrow immune ...

ABSTRACT: Many diseases are linked to abnormalities of gene expression patterns, and therefore, the study of drugs that alter gene expression patterns is important for improving these diseases. In ...

This study presents valuable findings with practical and theoretical implications for drug discovery, particularly in the context of repurposing cipargamin CIP for the treatment of Babesia spp. The ...