Proceedings of the National Academy of Sciences (PNAS)

A light-powered painkiller paves the way for opioids with fewer side effects

Researchers developed a molecule targeting the mu opioid receptor (at left, binding to morphine) that can be controlled with ...
Proceedings of the National Academy of Sciences (PNAS)

Isotopic evidence of dissolved organic nitrogen production and consumption in ocean surface waters

Unlike dissolved inorganic nitrogen, which is scarce in much of the tropical, subtropical, and temperate surface ocean, ...
Proceedings of the National Academy of Sciences (PNAS)

Catalytic reactive-hydrogen membranes for rapid capture and hydrodefluorination of six PFAS of regulatory concern

Per- and polyfluoroalkyl substances (PFAS) persist in aquatic environments due to their ultrastable C–F bonds and poor susceptibility to ...
PNAS

Correction for Johnson et al., Antagonistic regulation of nitrogen and drought signaling mediated by NIN-like protein 7 transcription factor in Arabidopsis thaliana

Correction for Johnson et al., Antagonistic regulation of nitrogen and drought signaling mediated by NIN-like protein 7 transcription factor in Arabidopsis thaliana ...
PNAS

Reply to Roff: Ecological readiness must evolve with AI

I thank Roff for extending the discussion on AI in ecology and agree that ecologists should actively shape how AI develops and is used (1). The growing use of AI in automated monitoring, remote ...
PNAS

Reply to Li & Zhang: Adaptive evolution of stop-loss RNA editing in Fusarium graminearum

We appreciate Li & Zhang’s efforts to distinguish adaptive editing from molecular error. Our conclusion does not imply that every stop-loss editing event is ...
PNAS

Ecology must shape AI before AI reshapes ecology

Publication trend in ecological studies with AI, based on Web of Science searches following (4). The vertical dashed line marks the endpoint of the original 2011–2022 dataset (4). Extending the search ...