Established environmental risk factors and common genetic variants do not explain the rising incidence of early-onset colorectal cancer.

Early 5-aminosalicylate use in pediatric Crohn disease is linked to reduced durability of future biologic therapy and higher corticosteroid exposure.

Caffeinated energy drink and stimulant supplement exposures were associated with disproportionate adverse cardiovascular event reporting.

Among adults with T2D and high BP, an intervention of MTM was effective for improing diet quality, even with gradual down dosing.