The weather outside was frightful at Highmark Stadium in Orchard Park, New York on Sunday night, but the way the San ...

The situation for the San Francisco 49ers is so dire that Brock Purdy had to send a clear and forceful message to his teammates. He also took ownership of personal mistakes in the recent loss, all ...

The San Francisco 49ers suffered another crushing defeat Sunday night, falling 35-10 to the Buffalo Bills. The loss marked ...

Josh Allen scored a receiving touchdown on a pass he threw in his latest do-everything performance, and the Buffalo Bills ...

The 49ers were absolutely shellacked Sunday for a second straight week as the Buffalo Bills beat them 35-10 on national ...

San Francisco 49ers star running back Christian McCaffrey departed Sunday night's snow game against the Buffalo Bills early ...

Buffalo Bills outside linebacker Greg Rousseau chases down San Francisco 49ers quarterback Brock Purdy to boosts his 2024 NFL ...

Follow along for updates throughout the game as the Buffalo Bills take on the San Francisco 49ers at snowy Highmark Stadium.

After three strong weeks of play from 49ers RB Christian McCaffrey, he left the game against the Bills after suffering a knee ...

Christian McCaffrey is dealing with an injury again. The 49ers running back went down with a knee injury in the second ...

Even though the NFL playoffs are more than a month away, a playoff atmosphere — and a playoff feel with the weather — will ...

Brandon Allen is 2-8 in 10 career starts. One of them was against Josh Allen and the Bills but Brandon Allen wore No. 2 in ...