Buffalo Bills outside linebacker Greg Rousseau scoops up a fumble recovery as San Francisco 49ers quarterback Brock Purdy ...

Christian McCaffrey is dealing with another long-term injury again. The San Francisco 49ers running back went ...

The tragedy of this 49ers’ season epitomized. For the first time since returning to the lineup in Week 10, McCaffrey looked ...

Josh Allen scored a receiving touchdown on a pass he threw in his latest do-everything performance, and the Buffalo Bills ...

Leading the way once again was the Bills’ quarterback, who was responsible for three of his team’s five touchdowns. ...

San Francisco 49ers quarterback Brock Purdy is poised to return to action on Sunday night against the Buffalo Bills after ...

The 49ers look to turn around their season with a win in Buffalo against the Bills, who are chasing the top seed in the AFC.

If you didn't know the San Francisco 49ers were Super Bowl contenders last season, you might not believe it now. The 5–6 team ...

Before the 2024 NFL season, Sunday night's Week 13 matchup between the Buffalo Bills and San Francisco 49ers might've been ...