San Francisco's Christian McCaffrey and George Kittle pose challenges for Houston's defense, and 49ers' pass rush will be key ...

The San Francisco 49ers enter Week 8 facing renewed questions about the health of their starting quarterback, Brock Purdy.

Kickoff from NRG Stadium is set for 1 p.m. ET, and the Texans are 1.5-point favorites, according to the latest 49ers vs.

Our expert Week 8 NFL predictions expect the 49ers to cover the spread behind All-Pro running back Christian McCaffrey!

Oct 19, 2025; Santa Clara, California, USA; San Francisco 49ers running back Christian McCaffrey (23) celebrates after a ...

NFL Week 8 odds, picks, predictions, TV channel, streaming information for the Sunday football game between San Francisco ...

The win helped the 49ers keep pace with the Los Angeles Rams (5-2) in the NFC West, with the possibility that still another ...

The Atlanta Falcons traveled to Santa Clara, California to take on the San Francisco 49ers on "Sunday Night Football." Here's ...

The Falcons and 49ers game will kick off at 8:20 p.m. ET on Sunday, Oct. 19. The San Francisco 49ers vs. Atlanta Falcons game ...

My Week 7 picks went 20-10 overall and included correct upset picks of the Colts over the Chargers and the Cowboys over the ...

A few of the best player props for Sunday night’s week seven game between the Atlanta Falcons and the San Francisco 49ers.

Atlanta Falcons linebacker Divine Deablo injured his forearm in the second quarter against the San Francisco 49ers and has ...