The San Francisco 49ers enter Week 8 facing renewed questions about the health of their starting quarterback, Brock Purdy. The 2025 season has already tested the team’s depth and resilience, with Purdy’s absence stretching the offense and forcing head coach Kyle Shanahan to make adjustments.

Kickoff from NRG Stadium is set for 1 p.m. ET, and the Texans are 1.5-point favorites, according to the latest 49ers vs. Texans odds. The over/under for total points scored is 42. Before you make any Texans vs. 49ers picks, make sure to check out what the SportsLine Projection Model has to say.

Oct 19, 2025; Santa Clara, California, USA; San Francisco 49ers running back Christian McCaffrey (23) celebrates after a touchdown during the second quarter against the Atlanta Falcons at Levi's Stadium. Mandatory Credit: Kyle Terada-Imagn Images / Darren Yamashita-Imagn Images

The San Francisco 49ers wrapped up their Week 5 game Thursday night, but they still picked up some wins Sunday.

The NFL trade deadline is right around the corner, and the San Francisco 49ers could make a move or two for a playoff push.

A few of the best player props for Sunday night’s week seven game between the Atlanta Falcons and the San Francisco 49ers.

Atlanta Falcons linebacker Divine Deablo injured his forearm in the second quarter against the San Francisco 49ers and has been ruled out for the remainder of Sunday's contest. Deablo signed with the team in free agency but has been arguably the most consistent player from week to week in his first season with the Falcons.

The San Francisco 49ers and the Tampa Bay Buccaneers square off in Week 6 of the NFL regular season. Here's the start time and where to watch.

They will head out on the road to face off against the Arizona Cardinals at 4:05 p.m. ET at State Farm Stadium. The 49ers will be looking to extend their current five-game winning streak. Last Sunday,

Mac Jones continues under center for the 49ers (5-2) when they travel to Houston for a Sunday afternoon tilt against the Texans (2-4). Despite being one of the most banged-up teams in the NFL, San Francisco sits tied atop the NFC West with the Seahawks and the Rams.