Inhibiting a problematic protein helps immunotherapies, CAR T-cell therapy to fight off melanoma more effectively

The first-of-its-kind study shows that adding a small molecule that blocks the problematic protein to existing cancer ...

AI model predicts peptide sequences that prevent ribosome stalling in E. coli protein production

Proteins sourced from microorganisms are attracting attention for their potential in biomanufacturing a variety of products, ...

Ancient protein Dicer and RNase H are both needed to resolve transcription–replication collisions, study reveals

Could yeast and humans be any more different? Going by looks alone, probably not. But peering into our genomes reveals ...
IEEE

Multimodal Contrastive Learning for Protein–Protein Interaction Inhibitor Prediction

Abstract: Protein-protein interactions (PPIs) are crucial for various cellular activities and disease development, and modulating PPIs using small molecule inhibitors (PPIIs) has gradually become a ...

New antivirals could help prevent cold sores by changing cell structures

A class of antivirals called Pin1 inhibitors could reduce or stop outbreaks of herpes simplex virus 1 (HSV-1), the common ...