In the nervous system, the intracellular chloride concentration ([Cl −] i) determines the strength and polarity of γ-aminobutyric acid (GABA)-mediated neurotransmission. [Cl −] i is determined, in ...

This is a preview. Log in through your library . Abstract The Resistance to Dieldrin gene, Rdl, encodes a GABA-gated chloride channel subunit that is targeted by cyclodiene and phenylpyrazole ...

Neuronal excitability is fundamental to neuronal function and is primarily controlled by a fine balance between synaptic excitation and inhibition. In the mammalian CNS, synaptic excitation is chiefly ...

The invertebrate glutamate-gated chloride-selective receptors (GluClRs) are ion channels serving as targets for ivermectin (IVM), a broad-spectrum anthelmintic drug used to treat human parasitic ...