Author: Steven Gulevich, MD; Chief Editor: Nicholas Lorenzo, MD, CPE, MHCM, FAAPL more ...

Cyanosis is a bluish or purplish tinge to the skin and mucous membranes. (See the images below.) Cyanosis. Facial cyanosis in a patient with chronic hypoxemia. Courtesy of BioMed Central Ltd, Springer ...

Author: Christopher R Gorman, MD; Chief Editor: William D James, MD more ...

Calcium pyrophosphate deposition (CPPD) disease is a metabolic arthropathy caused by the deposition of calcium pyrophosphate dihydrate in and around joints, especially in articular cartilage and ...

Pediatric gastroenteritis is an inflammation of the stomach and intestines most frequently caused by viral, bacterial, or parasitic infections and clinically characterized by the rapid onset of ...

The following organizations have released guidelines for the management of psychogenic nonepileptic seizures (PNES). Key diagnostic and treatment recommendations have been reviewed and integrated ...

Grade A (ie, strongly supported) treatment recommendations included the following. Immunocompetent patients - Topical azoles once or twice daily for 2-4 weeks; selenium sulfide once daily for 3 days, ...

American Urology Association (AUA) guidelines for diagnosis and management of genitourinary injuries were amended in 2017 and 2020 to reflect literature that was released since the original ...

Colon cancer is staged using the American Joint Committee on Cancer (AJCC) tumor/node/metastasis (TNM) classification and staging system. In this system, stages are assigned on the basis of the ...

The American Joint Committee on Cancer (AJCC) provides two principal groups for breast cancer staging: anatomic, which is based on extent of cancer as defined by tumor size (T), lymph node status (N), ...

Infectious Diseases articles covering symptoms, diagnosis, epidemiology, treatment, prognosis, and follow-up. Peer reviewed and up-to-date recommendations written by leading experts.

Renal disease (serum creatinine level ≥1.5 mg/dL in males or ≥1.4 mg/dL in females) If possible, avoid drugs that inhibit the enzyme cytochrome P450 3A4 (CYP3A4), such as ketoconazole, itraconazole, ...