The scope of human cell type atlases widened considerably today. Formerly, landscapes of individual cell types were largely confined to single organs. But now, thanks to four single-cell RNA ...

Genetic studies have revealed many genes linked to both common and rare disease, but to understand how those genes bring about disease and use those insights to help develop therapies, scientists need ...

Integrating gene expression across tissues and cell types is crucial for understanding the coordinated biological mechanisms that drive disease and characterize homoeostasis. However, traditional ...

In recent years, a virtual tidal wave of studies linking the expression of certain genes to complex diseases as varied as cancer and diabetes has raised hopes for major advances in medical treatment ...

Compared to cellular and organismal homeostasis, tissue homeostasis is not yet well understood. (Medzhitov) Cells have three division-of-labor relationships: (1) cell types perform different functions ...

Housekeeping protein-coding genes are stably expressed genes in cells and tissues that are thought to be engaged in fundamental cellular biological functions. They are often utilized as normalization ...

The average adult male has around 36 trillion cells in their body, while average adult females have 28 trillion, researchers have found. Unexpectedly, the mass of small cells in our bodies, such as ...