Genetic variants encompass single‐nucleotide changes, insertions, deletions and larger structural differences in DNA that influence gene function and regulation. The analysis of complex traits—such as ...

A new study has developed a powerful computational method that can detect how genes interact with each other to influence complex traits in humans at a scale previously impossible. The new method was ...

Predicting observable traits from genetic variation remains difficult due to the complex interplay of multiple genes and environmental influences. Widely used statistical approaches are limited in ...

Today's biomedical researchers are relentlessly searching for genes that drive disease, with the goal of creating therapies that target those genes to restore health. When a single gene is the culprit ...

Northwestern University biophysicists have developed a new computational tool for identifying gene combinations underlying complex illnesses such as diabetes, cancer, and asthma. Unlike single-gene ...

There are individuals who carry the same deletion of chromosome 16, and those same delections can lead to a wide range of potential neurodevelopmental issues in carriers, from milder mental illnesses ...

Our parents' genes, even the ones we didn't inherit, leave a measurable lasting imprint on our lives. An international team led by researchers at the Institute of Science and Technology Austria (ISTA) ...

Click here to view Volume I of this Research TopicThe domestication of animals and plants during the early Holocene marked a pivotal transition that led to ...

Nine species of sea snakes have now been identified as having regained the genetic requirements for advanced color vision, demonstrating that once a complex trait has been lost to evolutionary time, ...