Multiple myeloma has undergone a therapeutic revolution at a pace nearly unmatched in oncology. Yet amid these advances, a key assumption in multiple myeloma therapy persists: more and longer ...

Whether endovascular therapy benefits patients with mild acute ischemic stroke from large-vessel occlusion involving the ...

In adults with symptomatic severe aortic stenosis, aortic-valve replacement (AVR) relieves symptoms and improves survival. 1-3 Over the past 20 years, more information about the progression of aortic ...

The U.S. health care system still can’t identify medical harm as it occurs. But it’s now possible to develop systems that correct their own deficiencies and make improvements that matter to patients.

When we become obsessed with finding the right answer, at the risk of oversimplifying the richly iterative and evolutionary nature of clinical reasoning, the result is the very antithesis of ...

Although international guidelines recommend intrauterine insemination (IUI) with ovarian stimulation as first-line treatment for unexplained infertility, evidence from comparisons of this method with ...

Clinicians in Puerto Rico sometimes provide abortion care to people who travel to obtain services that are no longer provided in their home states. Yet residents themselves face high barriers to care.

Explore this issue of The New England Journal of Medicine (Vol. 393 No. 20).

When patients, or the parents of patients, become heavily invested in searching for someone to blame for an illness, it’s useful to ask what the search is doing for them. Its accuracy is rarely ...

Agencies have long relied on civil monetary penalties to address violations of health care and public health regulations. But rules governing federal fines are now in flux.

Explore this issue of The New England Journal of Medicine (Vol. 392 No. 10).