A man in his early 80s presented with transfusion-dependent macrocytic anaemia, steroid-responsive headaches and recurrent inflammatory flares. Broad infectious, autoimmune and haematological ...

Somatic mutations are changes to the DNA sequence that arise in non-reproductive cells during a plant’s lifetime, generating genetic mosaicism within leaves, stems and roots. In plants, the absence of ...

In this Innovation Spotlight, Peter Campbell, the cofounder and chief scientific officer of Quotient Therapeutics discusses a new somatic genomics platform built to identify these mutations and ...

Two new studies from Karolinska Institutet in Sweden have investigated how mutations that occur in muscles and blood vessels over time can affect aging. The studies, which are published in Nature ...

The relation between body mass index, comorbidity, choice of surgery, and prognostic factors in early breast cancer: Data from a nation-wide Danish cohort No significant financial relationships to ...

Preliminary safety data of the PRODIGE 81-FFCD 2101-TRIPLET-HCC trial assessing the triple combination atezolizumab-bevacizumab-ipilimumab in patients (pts) treated in systemic therapy for ...

Cardiovascular death had a strong tie to the somatic mutations that often accrue with aging in people with subclinical atherosclerosis, an observational study found. For asymptomatic people who had ...

Discussion of the potential of using pluripotent stem cells for tissue transplantation has raised issues about the frequency and types of spontaneous mutation in these cells. In the March 19 ...

It's a fundamental principle of science: Correlation does not equal causation. Every cancer cell has genetic mutations, but ...