Scientists can peer into cells to get a limited view of their activity using microscopes and other tools. However, cells and ...

High background noise in RNA samples can impact read accuracy and increase sequencing costs. Optimizing sample quality enables better microRNA mapping and more reliable insights in transcriptomics and ...

RNA sequencing has emerged as a powerful supplement to DNA sequencing for Mendelian disease diagnosis, but clinical translation of diagnostic RNA-seq has not been widely achieved. Researchers at ...

Essentially all cells in an organism's body have the same genetic blueprint, or genome, but the set of genes that are actively expressed at any given time in a cell determines what type of cell it ...

A research team led by Associate Professor Hirofumi Nishizono and graduate student Masaki Kato from the Research Support ...

Essentially all cells in an organism's body have the same genetic blueprint, or genome, but the set of genes that are actively expressed at any given time in a cell determines what type of cell it ...

Alzheimer’s disease (AD) and related dementias present significant challenges in therapeutic development, particularly within ...

April 14, 2025 – Genome Research (https://genome.org) publishes a second special issue highlighting advances in long-read sequencing applications in biology and medicine. In this second Special Issue, ...

Our results demonstrate that differential connectivity analysis reveals significant transcriptional alterations that are not detected by differential ...

Key opportunities lie in next-generation sequencing methods, with hospitals as major end-users and North America as a ...