Researchers have developed a novel technique that allows them to dial up or tone down the amount of a certain metastatic protein inhibitor (BACH1) within a cell. This could provide a new path in ...
A collaborative research group has developed a novel therapeutic candidate that may improve the prognosis of severe cutaneous ...
July 13, 2010 (Los Angeles, California) — An investigational compound that acts as a heat shock protein (HSP) inhibitor has shown promise in the treatment of lung cancer and in many other malignancies ...
While anti-VEGF therapies remain the current standard of care, many DME patients experience suboptimal responses due to ...
Combining proteasome inhibitors with autophagy inhibitors disrupts acute myeloid leukemia (AML) cells' proteostasis, ...
Preclinical study showed PDIA1 and PDIA5 protect cells from oxidative stress, maintain mitochondrial function, and are ...
This study is carried out by Prof. Qiang Liu (Breast Tumor Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University). In this study, researchers found that the palbociclib-resistant breast cancer ...
When many cancers advance, spread and reoccur, checkpoint inhibitors can help keep difficult tumors at bay. These antibody-based immunotherapies can restore the body’s ability to recognize and ...
PTKs play a crucial role in many cell regulatory processes such as mitogenesis, differentiation and development, oncogenesis, angiogenesis, cell survival and apoptosis, cell shape and adhesion, cell ...
The health impacts of a complex protein that plays a major role in the development of Alzheimer's disease and heart conditions can be lessened by three kinds of drug inhibitors, according to ...
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