Proteins that are no longer needed, defective, or potentially harmful are labeled with a molecular "tag" and dismantled in ...

EpiBiologics launched in 2023 with a $50 million series A, having been founded to take forward the work of renowned antibody ...

The startup is developing a medicine that can very specifically degrade cancerous forms of EGFR, the target of an array of ...

A new active substance attacks a key protein in tumor cells, leading to complete degradation. In cell experiments, this caused cancer cells to lose their protection and die. The active substance was ...

Enodia Therapeutics, a biotechnology company developing novel small-molecule therapies for targeted protein degradation at the point of synthesis, today announced it has raised 20 ...

Protein homeostasis is vital for healthy cells. It enables cells to rapidly initiate and terminate signaling pathways and allows for cell proliferation, growth, and differentiation. Disruption of this ...

Targeted protein degradation has moved well beyond its prologue more than 20 years ago. 1 The number of publications describing different PROTACs (PROteolysis TArgeting Chimeras), molecular glues, and ...

Targeted protein degradation (TPD) therapy is a promising new class of targeted treatments. Based on a cell’s natural mechanism for eliminating diseased proteins, this therapy can combat hard-to-treat ...

Discover how advanced detectors are driving improvements in biopharma quality assurance by enhancing precision across ...

The deal hands Amgen a drug that destroys two proteins known to drive certain types of acute myeloid leukemia, a profile that ...

Targeted protein degradation is a therapeutic strategy that utilizes the cell’s natural machinery to eliminate disease-causing proteins. The field traces its origins to the development of thalidomide ...