BUFFALO, N.Y. — When you pop a prescription pill into your mouth, you trust it to address the issue it was meant to fix. But what really happens? How is your body processing the drugs and what happens ...

The pharmacokinetics and pharmacodynamics of digoxin alone and digoxin plus zaleplon were studied. Healthy, nonsmoking men between 18 and 45 years of age were given a single oral dose of digoxin 0.375 ...

Association of Wnt pathway activation with prechemotherapy abiraterone acetate resistance in metastatic castration-resistant prostate cancer (mCRPC) by genome-wide analysis of metastases. This is an ...

SCT800 is a new third-generation recombinant FVIII agent that is undergoing promising preclinical study. This study aimed to investigate the pharmacokinetic and pharmacodynamic profiles of SCT800 in ...

To evaluate the pharmacokinetics (PK), pharmacodynamics (PD) and primary tolerability of an anti-CD11a monoclonal antibody (CMAB001) in Chinese healthy volunteers and psoriatic patients. Two ...

Communication in End-of-Life Cancer Care: A Comparison of Team Assessments in Three European Countries PURPOSE: To explain the variability of docetaxel pharmacokinetics through study of CYP3A ...

The pharmacokinetics and pharmacodynamics of lansoprazole suspension and lansoprazole capsules were studied. Thirty-six healthy males and females were randomized in a single-dose, open-label, ...

This review summarizes key data illustrating the clinical importance of pharmacodynamics, particularly among the fluoroquinolone family of antibacterials. Antibacterials are often divided into 2 ...

Both ABP-671 and ABP-745 have the potential to give gout patients more effective and safer alternatives to existing gout therapies.

Anaphylm™ (epinephrine) Sublingual Film is a polymer matrix-based epinephrine prodrug product candidate. Anaphylm is similar in size to a postage stamp, weighs less than an ounce, and begins to ...

The Phase III placebo-controlled, randomised, double-blind study is evaluating ADX-324's efficacy in adults with HAE.

Intervention/Treatment: The study tests ALN-5288, an experimental drug administered intrathecally, designed to evaluate its safety and effects in treating Alzheimer’s Disease. Participants will ...