ADME is the abbreviation for Absorption, Distribution, Metabolism and Excretion. ADME studies are designed to investigate how a chemical (e.g., a drug compound) is processed by a living organism.

In a study posted to the bioRxiv* preprint server, researchers studied the preclinical pharmacokinetics (PK) and in vitro absorption, distribution, metabolism, and elimination (ADME) properties of ...

Variability in pharmacokinetics and drug response is shaped by single-nucleotide variants (SNVs) as well as copy-number variants (CNVs) in genes with importance for drug absorption, distribution, ...

It may sound harsh, but drug candidates that are bound to be poor performers should be identified sooner rather than later—and ruthlessly eliminated from development. Granted, early in development, ...

Collaboration aims to create the first “organ-on-a-chip” system specifically designed for human PK predictions WOBURN, Mass.--(BUSINESS WIRE)-- Javelin Biotech (“Javelin”) today announces a three-year ...

Admescope has acquired Swedish contract research organization MetaSafe AB, which focuses on metabolic research and drug biotransformation. Financial terms were not disclosed. Oulu, Finland-based ...