Phase I pharmacokinetic study of multicycle high-dose carboplatin followed by peripheral-blood stem-cell infusion in patients with cancer. 9-AC lactone and total (lactone plus carboxylate) plasma ...
Devyani Deshpande, Jotam G. Pasipanodya, Stellah G. Mpagama, Shashikant Srivastava, Paula Bendet, Thearith Koeuth, Pooi S. Lee, Scott K. Heysell, Tawanda Gumbo ...
The pharmacokinetics and pharmacodynamics of digoxin alone and digoxin plus zaleplon were studied. Healthy, nonsmoking men between 18 and 45 years of age were given a single oral dose of digoxin 0.375 ...
BUFFALO, N.Y. — When you pop a prescription pill into your mouth, you trust it to address the issue it was meant to fix. But what really happens? How is your body processing the drugs and what happens ...
Current U.S. physician practices and attitudes in the treatment of peripheral T-cell lymphoma (PTCL). Background: Peripheral T-cell lymphoma (PTCL) has poor prognosis and there is no standard ...
SCT800 is a new third-generation recombinant FVIII agent that is undergoing promising preclinical study. This study aimed to investigate the pharmacokinetic and pharmacodynamic profiles of SCT800 in ...
CDR-Life announces early clinical data demonstrating pharmacodynamic activity of CDR404: Zurich, Switzerland Saturday, October 25, 2025, 18:00 Hrs [IST] CDR-Life, Inc, a biotechno ...
Ten subjects received continuous, intravenous infusion of higenamine at gradually escalating doses from 0.5 to 4.0 μg·kg −1 ·min −1, each dose was given for 3 min. Blood and urine samples were ...
Previous studies have shown that lansoprazole granules can be effectively administered when suspended in acidic soft foods or fruit juices. [13,14,15,16,17] However, administration of lansoprazole or ...
The pharmacodynamic process of drug therapy provides the link between the pharmacokinetic profile and the therapeutic effect of a drug. It encompasses how the drug produces the required ...
The study assessed OV329 in 68 healthy subjects, comprising 51 individuals receiving active treatment and 17 receiving placebo.
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