Mapping how Narcan reverses opioid overdose can provide a molecular blueprint for developing more effective drugs against ...

To date, therapies for multiple sclerosis (MS) focus on modifying or suppressing the immune system rather than on remyelination. Recent findings have pointed to the κ-opioid receptor (KOR) as a ...

Drugs that target opioid receptors sometimes have severe side effects. Thousands of people around the world die every day from overdoses involving opioids such as fentanyl. Researchers have taken a ...

– Study met primary endpoint demonstrating cebranopadol is significantly less abusable than oxycodone when taken intranasally (i.e., snorted) with majority of patients indicating no desire to take ...

Researchers have revealed a previously unknown function of opioid receptors in the development of the enteric nervous system (ENS), often referred to as the 'brain in the gut.' This discovery ...

Researchers at Rice University have revealed a previously unknown function of opioid receptors in the development of the enteric nervous system (ENS), often referred to as the "brain in the gut." This ...

The global burden of anxiety- and depression-related disorders is on the rise. While multiple drugs have been developed to treat these conditions, current medications have several limitations, ...

Opioid antagonists are medications people can take to treat opioid use disorder. They help by reducing withdrawal symptoms, addressing cravings, and managing overdoses. Doctors prescribe opioid ...