Researchers of the Melnick Lab, led by Prof. Ari Melnick, medicine, recently published a study identifying a key mutation that disrupts the B-cell natural selection process during immune response, ...

Dysfunction resulting from mitochondrial DNA mutations has been implicated in multiple human pathologies, including ...

As our body ages, cells have to divide to replenish those that become worn out or damaged. Most cells also carry the genome in their nucleus, which has to be replicated each time cell division takes ...

Genetic disorders can occur due to mutations in one gene (monogenic), multiple genes (multifactorial inheritance), and mutation in one or more chromosomes. Point mutations are where one nucleotide in ...

Gene therapy has the potential to dramatically benefit patients with genetic blood disorders, but a small study on participants in a clinical trial for sickle cell disease suggests that a key process ...

The influenza (flu) virus is constantly undergoing a process of evolution and adaptation through acquiring new mutations. Scientists at St. Jude Children's Research Hospital have added a new layer of ...

New research published in Nature Communications into hidden mutations in mitochondrial DNA has uncovered how high mutational levels coincide with later life and link to aging markers. Mitochondria are ...