"To investigate the mechanisms driving local TDP-43 accumulation, we combined human ALS biopsies, transgenic mouse models, and neuron–muscle co-cultures grown in microfluidic chambers that allow us to ...
Diverse combinations of glutamate receptor subunits are expressed across developmental stages and even between adjacent ...
A new research paper titled "AAV1.NT-3 gene therapy prevents age-related sarcopenia" has been published in Aging. Sarcopenia is progressive loss of muscle mass and strength occurring during normal ...
A skeletal muscle isn’t much use without a signal telling it to move. In vertebrates, this signaling happens at the neuromus-cular junction (NMJ), a synaptic connection between motor neurons and ...
Contract development and manufacturing organisation (CDMO) Andelyn Biosciences has entered a collaboration with Amplo Biotechnology to manufacture adeno-associated virus (AAV) gene therapies to ...