Repatha’s active ingredient, evolocumab, is a human monoclonal IgG2 that blocks an important protein in the body. Liver cells have specific receptors (“catchers”) on their surface. Their job is to ...

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Repatha works by blocking a specific enzyme in your liver to help your body remove cholesterol more effectively. It is not an immunosuppressant drug, so it doesn’t work by suppressing the immune ...

You can inject Repatha into the abdomen, thigh, or upper arm. It’s injected subcutaneously (under the skin). If you’re injecting it into your upper arm, you may need a family member or caregiver to ...

You can inject Repatha (evolocumab) at any time of day that’s convenient for you. The manufacturer doesn’t recommend a best time of day to inject Repatha. The time you choose won’t alter the drug’s ...