The development and spread of antibiotic resistance represents one of the greatest threats to global health. To overcome these resistances, drugs with novel modes of action are urgently needed.

More and more bacterial pathogens are developing resistance. There is an increasing risk that common drugs will no longer be effective against infectious diseases. That is why scientists around the ...

There is a compelling need to produce new antibiotics that hamper severe opportunistic infections, especially in immunocompromised individuals, such as those caused by gram-negative Pseudomonas ...

As more and more pathogenic bacteria gain resistance to commonly used antibiotics, the search for new, effective, and safe antibiotics has become vital. According to The Lancet, almost 5 million ...

The rise of antimicrobial-resistant pathogens has spurred scientists to search far and wide for new drugs. And while many antimicrobial molecules have been discovered in recent years, it’s rare to ...

Early-life exposure to antibiotics is associated with altered growth up to age 5, with the Augmentin-plus-gentamicin regimen ...

Without coordinated international action, combining antimicrobial stewardship, surveillance, and improved hygiene infrastructure, resistant bacteria will continue to spread unchecked. We urgently need ...

Fungal infections may not be as common as bacterial or viral infections, but they can still be deadly. And the deadliest pathogenic fungi, such as Candida auris, are becoming increasingly resistant to ...