MIT researchers discovered that the genome’s 3D structure doesn’t vanish during cell division as previously thought. Instead, ...

The APC/C (anaphase-promoting complex; also known as the cyclosome) is an E3 ubiquitin ligase that mediates the ubiquitylation of key substrates for their degradation by the proteasome at precise ...

Researchers say findings help to bridge the structure of the genome to its function in managing how genes are turned on and off.

MIT scientists have overturned the belief that genome structure vanishes during cell division. Using high-resolution genome ...

p21 Cip1 is a multifunctional protein and a key player in regulating different cellular processes. The transcription of p21 is regulated by p53-dependent and -independent pathways. The expression of ...

The growth and division of a cell is orchestrated into a highly controlled and ordered process called the cell cycle. The cell cycle contains 4 stages; Gap 1 (G1) phase, synthesis (S) phase, gap 2 (G2 ...

Proceedings of the Royal Society of London. Series B, Biological Sciences, Vol. 135, No. 879 (Jun. 1, 1948), pp. 233-242 (10 pages) As a preliminary study of the conditions which affect the hour to ...