How actin wavefronts rescue T cell receptors from endocytosis

Every time our body encounters a new disease-causing agent, a crucial defense system called adaptive immunity comes into play ...
The American Journal of Managed Care

Linking T-Cell Composition to CAR T Efficacy in Multiple Myeloma

Higher levels of CD4-positive naïve T cells in patients receiving CAR T-cell therapy for multiple myeloma are associated with ...
Fred Hutch

For many blood cancer patients, CAR T-cell therapy is game-changing

CAR T-cell therapy, which transforms patients’ own immune cells into cancer-fighting warriors, has revolutionized how physicians treat cancer, especially blood cancers. “These patients can be cured ...
The American Journal of Managed Care

CAR T-Cell Therapy Holds Potential in SCLC, but Significant Barriers Remain

CAR T-cell therapy shows promise for SCLC, but significant barriers, such as tumor heterogeneity and immunosuppression, must be addressed. Identifying tumor-selective antigens like CDH17, GD2, and ...