The global burden of anxiety- and depression-related disorders is on the rise. While multiple drugs have been developed to treat these conditions, current medications have several limitations, ...

See related article at Key points In this issue’s research article, Rebić and colleagues show that rates of opioid prescribing across 6 Canadian provinces declined gradually from 2018 to 2022, with n ...

The pain management field is currently driven by the urgent need to move beyond addictive opioids and treatment options than run the risk of toxicity at high doses, such as acetaminophen (APAP) and ...

July 11 (UPI) --While scientists have long noted a complex connection between a person's addiction to opiates, or "opioid use disorder," and chronic pain, the brain mechanisms linking the two have ...

Adolescents and young adults were at greater risk of using opioids if their parents had multiple opioid prescriptions, ...

Chronic pain affects more than 50 million Americans and remains one of the most difficult conditions to treat safely and effectively. While opioids have long been a cornerstone of pain management, ...

Tris Pharma Showcases a Novel Mechanism of Dual-NOP/MOP (NMR) Agonism for the Treatment of Moderate-to-Severe Acute Pain and Encores Positive Phase 3 Data at 2025 Annual PAINWeek Meeting in Las Vegas ...

Stop me if you’ve heard this one before: A miracle new painkiller promises to save us all from the scourge of addiction while ...