TRV045 shows potential for sustained, long-term analgesic effect in preclinical model of neuropathic pain, with no evidence of receptor desensitization TRV045 demonstrates statistically significant, ...

Virtually all new analgesics approved over the past 25 years are derivatives or reformulations of opioids or aspirin-like drugs, existing drugs given for a new indication or older drugs given by a ...

Regular use of aspirin has been linked to a lower risk of gastrointestinal and other cancers, though evidence for an association with brain tumors is mixed. We examined the association of aspirin and ...

Oxycodone HCl 4.8355mg, aspirin 325mg; scored tabs. Oxycodone is a full opioid agonist and is relatively selective for the mu receptor, although it can bind to other opioid receptors at higher doses.

Boston, MA - Regular use of common analgesics such as aspirin, acetaminophen, or nonsteroidal anti-inflammatory drugs (NSAIDs) appears to increase the risk of hypertension, according to a new study [1 ...

Neuropathic pain (NP) is defined as pain caused by injuries or diseases of the peripheral and central nervous system, according to the International Association for the Study of Pain 1. Estimation of ...

A study published in the Journal of Medicinal Chemistry presents a new family of candidate compounds for the treatment of Alzheimer's disease and pain, which have shown promising effects in animal ...

Prolonged use of nonsteroidal anti-inflammatory drugs (NSAIDs) or acetaminophen modestly increases the risk for hearing loss in older women, a prospective analysis of data from the Nurses' Health ...