An illustration of nerve cells affected by Lewy bodies in the brain of a patient with Parkinson's disease. The first detailed description of Parkinson's disease, published in 1817 by British physician ...

Researchers from Johns Hopkins Medicine and the Dana Farber Cancer Institute in Boston have shown that the hormone irisin, which is secreted into the blood during endurance, or aerobic, exercise, ...

Experiments in mice at Johns Hopkins Medicine suggest that the transmission of a toxic neuron-killing protein (α-syn) associated with Parkinson's disease originates among cells in the gut and travels ...

However, how pathological alpha-synuclein causes dopaminergic neuron death has been unclear.To pin down its role, Dawson and his colleagues used proximity labeling coupled with mass spectrometry to ...

Researchers from Johns Hopkins Medicine and the Dana Farber Cancer Institute in Boston have shown that a hormone secreted into the blood during endurance, or aerobic, exercise reduces levels of a ...

Neurons express Aplp1 (in white), a key protein that allows brain cells to absorb Parkinson’s-disease causing alpha-synuclein. In studies with genetically engineered mice, Johns Hopkins Medicine ...

Researchers have shown that a hormone secreted into the blood during endurance, or aerobic, exercise reduces levels of a protein linked to Parkinson's disease and halts movement problems in mice.