Drug discovery is shifting from static snapshots to moving pictures. Instead of inferring how medicines work from end results ...

A bitter taste receptor, TAS2R14, has been shown to respond to both extracellular and intracellular signals. Indeed, it can respond to both signals simultaneously. This finding is especially ...

Natural killer (NK) cells are pivotal in the innate immune response against cancer and viral infections, with their presence in tumors correlating to better patient outcomes in various cancers.

Natural killer (NK) cells are pivotal in the innate immune response against cancer and viral infections, with their presence in tumors correlating to better patient outcomes in various cancers.

Researchers at the University of North Carolina (UNC) at Chapel Hill School of Medicine have revealed the detailed structure of the bitter taste receptor, a protein called TAS2R14, and have shown ...

"Although more extensive studies are required to better understand the functional significance of TAS2Rs in cancer cells, we suggest that intracellular TAS2Rs act as chemosensory receptors that drive ...

A sugar on mycobacteria binds to the immune receptor dectin-1 on host macrophages, helping the bacteria survive and driving ...

Histamine is widely known for its role in allergic reactions but also functions as a key neurotransmitter in the brain, where ...

A research team from the Department of Bioscience, Faculty of Life Sciences, Okayama University of Science, has made a discovery: bitter taste receptors are present inside cancer cells and play a ...

The nonapeptide Oxytocin is a cyclic nine-amino‐acid peptide that has long been studied for its possible roles in ...