Cefazolin is a first‐generation cephalosporin widely used in the treatment of infections caused by methicillin-susceptible Staphylococcus aureus (MSSA). Its favourable safety profile and reduced risk ...

Mechanisms to explain the "inoculum effect" have not been elucidated in gram-positive infections. A mouse model of group A streptococcal myositis was used to compare the efficacies of two /β-lactams, ...

Beta-lactams are superior to vancomycin for definitive therapy, but not empiric treatment of methicillin-susceptible Staphylococcus aureus (MSSA) bloodstream infection, according to a large ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 73, No. 9 (Sep., 1976), pp. 3293-3297 (5 pages) Growth of E. coli at pH 5 protected the bacteria against the lytic ...

The researchers compared the effectiveness of oral beta-lactams to fluoroquinolones in the treatment of Enterobacteriaceae bloodstream infections (EBSI) in adult patients. This article is written live ...

Prolonged infusion of beta-lactam antibiotics for sepsis or septic shock tended to improve mortality compared with conventional intermittent infusion in the BLING III trial, and a meta-analysis ...

Among hospitalized patients with community-acquired pneumonia, those treated with azithromycin plus beta-lactams had lower in-hospital mortality and mortality rates at 30 and 90 days post-admission ...