Unique mutations in the H5N1 strain enhance replication in human cells and cause severe disease in mice. The virus has spread from birds to mammals, including dairy cows, and infected humans, with one ...

Researchers have discovered new regions of the human genome particularly vulnerable to mutations. These altered stretches of DNA can be passed down to future generations and are important for how we ...

The patient in Louisiana who was hospitalized with severe bird flu illness was found to have a mutated version of the virus, the U.S. Centers for Disease Control and Prevention (CDC) announced last ...

In their first few months of life, two siblings rapidly lost most of their body fat. Now, doctors have found the cause: a DNA mutation never previously linked to their underlying disease. People with ...

(Reuters) - The U.S. Centers for Disease Control and Prevention said on Thursday its analysis of samples from the first severe case of bird flu in the country last week showed mutations not seen in ...

Humanized mouse models are essential for investigating human gene function; however, the complete replacement of mouse genes ...

In a novel study, researchers introduced LoGoFunc, an advanced computational tool that predicts pathogenic gain- and loss-of-function variants across the genome. Unlike current methods that ...

Traditional biochemical methods of studying human gene mutations are often laborious and costly. Now bioengineers at the University of California San Diego have developed a new simple approach to ...

In 1992, Judith Frydman, PhD, discovered a molecular complex with an essential purpose in all of our cells: folding proteins correctly. The complex, a type of "protein chaperone" known as TRiC, helps ...

Proteome analysis with artificial intelligence has made it possible to create a catalog of all possible missense mutations in the human genome to predict diseases. The new Alphamissense tool from the ...