Cells have sophisticated methods of sensing stimuli and communicating with nearby cells in response to these stimuli. For example, macrophages can sense environmental stimuli—tissue damage, foreign ...

Autoimmune diseases stem from a complicated interplay of immune dysregulation, characterized by chronic inflammation and the loss of self-tolerance. Cytokines are central to these processes. These ...

Scientists in the Blavatnik Institute at Harvard Medical School and MIT have created a new family of tools that, for the first time, illuminates the missing half of how the immune system uses ...

Psoriasis, a chronic inflammatory skin condition characterized by dry and scaly skin lesions, affects about 7.5 million people in the United States. Psoriasis results from abnormal proliferation of ...

A collaborative research team has successfully developed designer enzymes that exhibit both intrinsic and extrinsic functions by transplanting a synthetic trinuclear zinc center into a human cytokine.

Cytokines are small proteins that serve as the fundamental chemical messengers of the immune system. They also play a key cell signaling role in stem cell biology, relaying messages that direct stem ...

People often get immunotherapy as a treatment for cancer. These immunotherapy treatments can be effective, but they may cause your immune system to have an unnatural response. Your body, as a result ...

Scientists optimize organoid culture growth and consistency with validated growth factor panels. Researchers can optimize organoid culture growth and consistency with panels of growth factors that are ...

Prior to the COVID-19 pandemic it may have been primarily researchers in labs and clinicians in intensive care units who were aware of a dangerous form of infection-triggered runaway inflammation ...

What is cytokine release syndrome? Cytokine release syndrome (CRS) is a side effect of some cancer treatments, particularly types of immunotherapy treatment. It is a reaction that causes inflammation ...