Structural analyses using cryogenic electron microscopy reveal how the versatile oncoprotein DEK binds nucleosomes, bends linker DNA, and coordinates histone modifications to regulate gene expression.

Researchers have discovered how the protein XPD detects severe DNA damage and controls its repair. The XPD protein is a central component of our body's own "DNA repair team," known as nucleotide ...

MSK researchers are shedding new light on G-quadruplexes, a type of secondary DNA structure that can cause DNA replication to stall. The structures are a potential therapeutic target in cancer. Image ...

Nearly 100 years ago, a seemingly simple discovery revolutionized the microscope. The introduction of phase-contrast, which garnered a Nobel Prize in 1953, brought into clear view structures inside ...

Integrative taxonomy combining mitochondrial DNA, comparative morphology, and egg scanning electron microscopy has revealed ...

Using a tiny, spherical glass lens sandwiched between two brass plates, the seventeenth century Dutch microscopist Antonie van Leeuwenhoek was the first to officially describe red blood cells and ...

Scanning transmission electron microscopy, or STEM, is a powerful imaging technique that enables researchers to study a material’s morphology, composition, and bonding behavior at the angstrom scale.

Scientists often describe life as a series of chemical reactions. Pallav Kosuri, Ph.D., describes life as movement. Chemical reactions are how you drive the movement of atoms, proteins, cells and ...

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Electron microscopes are used wherever particularly small details need to be imaged. But from a strictly physical point of view, every electron in a conventional electron microscope represents a ...