At one month, ticagrelor was not superior to twice-daily clopidogrel in reducing major adverse cardiovascular events (MACEs) ...

Baseline clinical characteristics were well balanced between the 2 groups (Table 1), and both groups received similar treatments following baseline angiography (Table 2). Although nonsignificant, ...

The antiplatelet drug clopidogrel helps prevent stent-associated thrombosis, but the antiplatelet effects are quite variable and the clinical consequences can be serious. New findings show that the ...

CHICAGO -- For prolonged antithrombotic treatment after percutaneous coronary intervention (PCI), clopidogrel monotherapy was more effective and at least as safe as aspirin monotherapy in a high-risk ...

Clopidogrel requires transformation into an active metabolite by cytochrome P-450 (CYP) enzymes for its antiplatelet effect. The genes encoding CYP enzymes are polymorphic, with common alleles ...

Antiplatelet therapy with the ADP P2Y12 receptor antagonist clopidogrel is recommended by current clinical practice guidelines to prevent atherothrombotic events in patients with coronary artery ...

April 10, 2009 (Boston, Massachusetts) — Smoking has become the latest factor shown to affect responsiveness to clopidogrel (Plavix, Bristol-Myers Squibb/Sanofi-Aventis), with a new post hoc analysis ...

The anti-blood clot regimen that adds the drug clopidogrel (Plavix) to aspirin treatment is unlikely to prevent recurrent strokes and may increase the risk of bleeding and death in patients with ...

The efficacy of clopidogrel in combination with acetylsalicylic acid (ASA) therapy has been clearly established in well-designed randomized controlled trials that have shown a reduction in recurrent ...

Friesen1 has provided thoughtful comments about the “loss of efficacy” of clopidogrel from grapefruit interactions that was reported in our article.2 Because clopidogrel is commonly prescribed in ...

San Francisco, CA—Despite the substantial incidence of atrial fibrillation (AF) in patients with valvular heart disease, there is a lack of data in the literature regarding optimal pharmacological ...