Cutaneous T-cell lymphoma, or CTCL, is one of the most stubborn malignancies in hematology and dermatology alike. The disease ...

An international research team has discovered a previously unknown mechanism that plays a key role in the signaling pathways ...

A combination treatment for advanced liver cancer appears to do something remarkable inside the tumor itself: it helps build ...

Our understanding of how cells interact with each other has been driven for decades by the central concept of ...

Most cell signals are chemical in nature. For example, prokaryotic organisms have sensors that detect nutrients and help them ...

The design of new calcium channels, built bottom-up from scratch, was reported last week in Nature. "Biochemists have been studying ion channels for decades and debating about how they work for almost ...

Researchers at the Stanford Cardiovascular Institute have characterized an unexpected signaling pathway that helps drive ...

Scientists have discovered a new nerve cell signaling mechanism could transform our understanding of pain and lead to safer, more effective treatments. The study, co-led by Matthew Dalva, a chair in ...

The cells lining skin capillaries are constantly sending each other messages—tiny pulses of calcium that help regulate blood flow, sense physical forces and keep vessel walls intact. Scientists have ...

The enzyme RNA polymerase II transcribes genes into messenger RNA. This process is guided by modifications to the enzyme's "tail" called phosphorylation patterns. Scientists at St. Jude Children's ...