Learn more about a new experimental procedure that uses cancer cells’ DNA repair system against itself to make drug-resistant ...

Cancer cells survive by repairing damage to their DNA—even damage that would normally be fatal. One of their most important ...

Researchers have captured detailed structural images of a DNA repair process called single-strand annealing, identifying a previously unseen intermediate stage. The study, using a yeast protein ...

Conceptual illustration showing how high transcriptional activity driven by super-enhancers can lead to DNA breaks at oncogenes. When these breaks are repaired inaccurately, they can give rise to ...

Scientists have captured the most detailed structural images to date of a specific type of protein's DNA repair process, a ...

A new hereditary condition has been discovered that affects patients' ability to repair DNA – leaving them both at greater risk of developing blood cancer, and unable to repair some of the damage ...

Therapeutic landscape of Rad51 in cancer treatment. Key elements include (1) DNA damage sources (PARPi, chemo/radiotherapy);(2) repair pathways (Rad51‐mediated HR); (3) intervention strategies (Rad51 ...

Relationship Among DNA Damage Response Gene Alterations, Molecular Subtypes, and Survival Outcomes in Patients With Metastatic Bladder Cancer Treated on CALGB 90601 Sequencing data from 56,965 ...

A troubling new study from MIT reveals that a common environmental contaminant, NDMA—found in polluted water, certain medications, and even processed foods—may pose a far greater cancer risk to ...