Metastases develop in 10–15% of patients with cutaneous melanoma and there is no evidence from phase-III trials that systemic treatment prolongs survival, nor is there an effective adjuvant therapy ...

An interpretable pathomics framework predicted BRAF V600E status in papillary thyroid carcinoma from routine Wright-stained ...

Brain tumors are the most common solid tumor of children and the most common cause of cancer-related deaths. The poor overall outcome of this patient population results from three major issues: 1) The ...

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Researchers have identified a range of genetic alterations in glioma brain cancers that will help them to understand how different mutations in one particular gene interact with other gene alterations ...

<?xml encoding="utf-8" ?> Nuvectis Pharma NVCT reported third-quarter financial results on Wednesday. The transcript from the company’s third-quarter earnings call has been provided below. This ...

Cathy Eng, MD, discusses a BREAKWATER post hoc analysis showing poorer survival in early-onset BRAF V600E colorectal cancer. Eng explained that BREAKWATER studied newly diagnosed patients with a BRAF ...

The BRAF mutation affects a small percentage of non-small cell lung cancer (NSCLC) cases, making the cancer more difficult to treat. In recent years, advances in treatment have helped to improve ...

BRAF-positive metastatic malignant melanomas develop resistance to treatment with drugs targeting the BRAF/MEK growth pathway through a major change in metabolism, new research shows. The findings ...

Researchers have discovered a signaling pathway between cytokines and BRAF that promotes tumor growth. The finding could provide a potential therapeutic target. The protein BRAF is a key player in the ...