In many bacteria, the DnaA protein, responsible for chromosome replication initiation, also acts as a transcription factor regulating its own gene expression and the expression of other loci. Here, we ...

Bacterial DNA replication is a highly coordinated process that ensures faithful genome duplication and cell division. Replication initiates at a single chromosomal origin (oriC) where multiple copies ...

When bacteria cells replicate, they do so a little differently than human cells do. They don’t undergo mitosis, a splitting that involves construction of spindles to carefully separate the DNA after ...

If you are anything like us, whenever you plan a journey, you spend a remarkable amount of time thinking about the start and the middle. Is everything packed? What time should we leave? Will there be ...

When bacteria cells replicate, they do so a little differently than human cells do. They don't undergo mitosis, a splitting that involves construction of spindles to carefully separate the DNA after ...

Structural biologists at the University of Wisconsin-Madison today published cryo-electron microscopy structures of the complete bacterial DNA replication restart complex — a molecular machine that ...