Among the challenges facing asymmetric synthesis the selective construction of quaternary stereogenic centres, particularly those bearing all-carbon substituents, stands out. The aldol reaction has ...
Figure 1: Bottom-up synthesis of hexoses from achiral starting materials via chemical or biocatalytic routes. In summary, we have developed a procedure for the preparation of a number of aldose ...
The Thermo Scientific picoSpin 45 NMR spectrometer is a useful tool for teaching through the aldol condensation reaction. In a number of undergraduate organic teaching programs, probably the first ...