Scientists at the Institute of Science Tokyo (Science Tokyo) have successfully realized the highly selective asymmetric 1,6 addition of aliphatic Grignard reagents to α,β,γ,δ-unsaturated carbonyl ...

The proposed method for anti-Michael addition in this study can enable one-step synthesis of α-substituted carbonyl compounds, which are commonly used in pharmaceuticals. Their study was made ...

A pair of chemists at Cornell University has extended the scope of carbonyl olefination reactions by developing a new electrophotocatalytic process. In their paper published in the journal Science ...

The organometallic synthesis of carbonyl compounds encompasses a broad array of methods that employ metal–carbon bonds to construct, modify or elaborate aldehydes, ketones, esters and related ...

The reaction utilizes an iron catalyst together with an N-heterocyclic carbene (NHC) ligand, which suppresses unwanted side reactions to promote highly selective nucleophile addition. In organic ...