The rematch of the national title from two years ago is huge for the playoff chase. Here’s the CFN Washington vs Michigan preview, prediction, and betting line.

Washington head coach Jedd Fisch is no stranger to Michigan football. In fact, Fisch was Jim Harbaugh's first (de facto) offensive coordinator in Ann Arbor, as the team's pass game coordinator. On Saturday, he'll make his first return to The Big House, albeit as the head coach of the opposition.

Washington visits Michigan on Saturday, bringing Huskies head coach Jedd Fisch back to the Michigan Stadium sideline for the first time since he worked with the Wolverines. Fisch, Michigan’s passing game coordinator and quarterbacks and wide receivers coach during Jim Harbaugh’s first two seasons (2015 and 2016), respects Michigan’s rich tradition.

While it has been overshadowed by Penn State's collapse, the first half of Michigan's season hasn't exactly gone to plan.

We'll see if the offense rebounds with a hungry Washington team coming to town, albeit for a kickoff at 9 a.m. on the body clock for the Huskies. Kickoff is at noon EDT at The Big House with the game set to be televised on Fox.

Michigan entered Los Angeles as the No. 15 team in the country and a team that thought it could contend for not only a Big Ten title, but a spot in the College Football Playoff. However, the Wolverines left the 31-13 loss to the Trojans with more questions than answers and Michigan fell out of the top 25.

Watch Michigan players react to the USC loss and share how they’ll fix discipline and tackling before Washington.

Sherrone Moore's Michigan will host Washington on Saturday as the Wolverines aim to improve to 5-2 on the 2025 season. Michigan fell 31-13 at USC last weekend and dropped out of the AP Top 25.

Pregame analysis and predictions of the Washington Huskies vs. Michigan Wolverines NCAAF game to be played on October 18, 2025 on ESPN.