It wouldn't be the first time Brohm has utilized multiple quarterbacks at Louisville. In 2004 as the quarterbacks coach under then-head coach Bobby Petrino, the Cardinals ran a two-quarterback system between senior Stefan LeFors and highly-touted true freshman (plus little brother and current quarterbacks coach/offensive coordinator) Brian Brohm.

The Miami Hurricanes come off a bye week to host Louisville in a Friday night game in South Florida. The Gators need a win at home vs. Mississippi St.

Louisville has a long history of high-powered offense. Coach Jeff Brohm has a much more balanced group of Cardinals these days.

Louisville and second-ranked Miami have had their share of shootouts over the years. Both teams can still score, but the Friday matchup in Miami Gardens, Fla., also will feature the Atlantic Coast Conference's top two defenses.

Mario Cristobal and Miami do not have a great late-season track record. Here's why this year could be different.

This article was originally published on www.si.com/college/louisville as Louisville Opens as Sizable Road Underdog at Miami. LOUISVILLE, Ky. - The Louisville football program will be heading down to Coral Gables to take on Miami on the other side of their bye week, and as expected, oodsmakers are tabbing them as significant underdogs.